{"id":3431,"date":"2025-07-14T14:17:07","date_gmt":"2025-07-14T14:17:07","guid":{"rendered":"https:\/\/tidolore.ch\/staging\/peripheral-neuropathies-diabetic-toxic-pharmacological\/"},"modified":"2026-04-04T19:23:29","modified_gmt":"2026-04-04T19:23:29","slug":"peripheral-neuropathies-diabetic-toxic-pharmacological","status":"publish","type":"post","link":"https:\/\/tidolore.ch\/staging\/en\/peripheral-neuropathies-diabetic-toxic-pharmacological\/","title":{"rendered":"Peripheral Neuropathies (Diabetic, Toxic, Pharmacological)"},"content":{"rendered":"\n<p>Peripheral neuropathy is a condition where the nerves in the arms and legs no longer function correctly. This can cause symptoms such as: <\/p>\n\n<ul class=\"wp-block-list\">\n<li>tingling,<\/li>\n\n\n\n<li>electric shocks,<\/li>\n\n\n\n<li>numbness,<\/li>\n\n\n\n<li>burning,<\/li>\n\n\n\n<li>persistent pain.<\/li>\n<\/ul>\n\n<p>When pain becomes a primary symptom, we refer to it as <strong>painful peripheral neuropathy<\/strong>.<\/p>\n\n<h2 class=\"wp-block-heading\"><strong>What are the most Common Causes?<\/strong><\/h2>\n\n<p>Neuropathies can have many causes. Among the most common are: <\/p>\n\n<ul class=\"wp-block-list\">\n<li><strong>Diabetes<\/strong> (very common),<\/li>\n\n\n\n<li><strong>Medication side effects<\/strong>, such as chemotherapy,<\/li>\n\n\n\n<li><strong>Nutritional deficiencies<\/strong> (e.g., vitamin B12),<\/li>\n\n\n\n<li><strong>Autoimmune diseases<\/strong>,<\/li>\n\n\n\n<li><strong>Certain infections<\/strong> (such as HIV or herpes zoster),<\/li>\n\n\n\n<li><strong>Genetic (hereditary) causes<\/strong>.<\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\"><strong>How Does it Affect Daily Life?<\/strong><\/h2>\n\n<p>Neuropathic pain can be continuous or &#8220;shock-like,&#8221; worsen at night, and make it difficult to:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>sleep well,<\/li>\n\n\n\n<li>walk,<\/li>\n\n\n\n<li>work,<\/li>\n\n\n\n<li>perform everyday activities.<\/li>\n<\/ul>\n\n<p>Additionally, many people with painful neuropathy also suffer from:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>anxietyo depression,<\/li>\n\n\n\n<li>chronic fatigue,<\/li>\n\n\n\n<li>social isolation.<\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\"><strong>How is it Treated?<\/strong><\/h2>\n\n<h3 class=\"wp-block-heading\">Personalized Approach<\/h3>\n\n<p>There is no single treatment that works for everyone. For this reason, we offer a <strong>tailored approach<\/strong> for each patient, which may include: <\/p>\n\n<h3 class=\"wp-block-heading\"><strong>Treatments<\/strong><\/h3>\n\n<ul class=\"wp-block-list\">\n<li><strong>Specific medications<\/strong>: such as gabapentinoids, low-dose tricyclic antidepressants (e.g., amitriptyline).<\/li>\n\n\n\n<li><strong>Physical therapy and rehabilitation<\/strong>: to maintain strength and mobility.<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/tidolore.ch\/staging\/en\/transcutaneous-electrical-nerve-stimulation\/\" data-type=\"post\" data-id=\"1851\">TENS<\/a> (Transcutaneous Electrical Nerve Stimulation)<\/strong>: a small device that sends painless electrical impulses to &#8220;calm&#8221; the nerves.<\/li>\n\n\n\n<li><a href=\"https:\/\/tidolore.ch\/staging\/en\/capsaicin-8\/\" data-type=\"post\" data-id=\"2497\"><strong>Capsaicin patch<\/strong> <strong>8% <\/strong><\/a><strong>(Qutenza\u00ae)<\/strong>: for localized neuropathic pain.<\/li>\n\n\n\n<li><strong>Psychological support<\/strong>: if pain affects mood or sleep.<\/li>\n\n\n\n<li><strong><a href=\"https:\/\/tidolore.ch\/staging\/en\/spinal-cord-neurostimulation\/\" data-type=\"post\" data-id=\"1703\">Spinal neuromodulation<\/a><\/strong>: electrical nerve stimulation through a small implant. This treatment is only considered if simpler therapies don&#8217;t work. <\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\">Note: Medications Alone are not Enough<\/h2>\n\n<p>Many patients with neuropathy use various medications but without satisfactory results. Sometimes medications cause side effects or are not tolerated. Therefore, it is important to:  <\/p>\n\n<ul class=\"wp-block-list\">\n<li><strong>avoid self-treatment<\/strong>,<\/li>\n\n\n\n<li><strong>avoid prolonged use of opioids<\/strong> (they are not effective for neuropathic pain),<\/li>\n\n\n\n<li><strong>seek specialist evaluation<\/strong> to develop a personalized treatment plan.<\/li>\n<\/ul>\n\n<h2 class=\"wp-block-heading\">What Does Research Say?<\/h2>\n\n<p>Recent studies show that:<\/p>\n\n<ul class=\"wp-block-list\">\n<li>Neuropathic pain has a significant impact on quality of life,<\/li>\n\n\n\n<li>Multimodal treatments (combining medications, physical therapy, psychological support, and neuromodulation) work better than medications alone,<\/li>\n\n\n\n<li>People with well-controlled pain can return to work, sleep better, and resume their activities.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Peripheral neuropathy is a condition where the nerves in the arms and legs no longer function correctly. This can cause symptoms such as: When pain becomes a primary symptom, we refer to it as painful peripheral neuropathy. What are the most Common Causes? Neuropathies can have many causes. Among the most common are: How Does [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3432,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45],"tags":[],"class_list":["post-3431","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sindrome"],"rttpg_featured_image_url":{"full":["https:\/\/tidolore.ch\/staging\/wp-content\/uploads\/2025\/07\/Painful-Feet-scaled.jpg",2560,1920,false],"landscape":["https:\/\/tidolore.ch\/staging\/wp-content\/uploads\/2025\/07\/Painful-Feet-scaled.jpg",2560,1920,false],"portraits":["https:\/\/tidolore.ch\/staging\/wp-content\/uploads\/2025\/07\/Painful-Feet-scaled.jpg",2560,1920,false],"thumbnail":["https:\/\/tidolore.ch\/staging\/wp-content\/uploads\/2025\/07\/Painful-Feet-150x150.jpg",150,150,true],"medium":["https:\/\/tidolore.ch\/staging\/wp-content\/uploads\/2025\/07\/Painful-Feet-300x225.jpg",300,225,true],"large":["https:\/\/tidolore.ch\/staging\/wp-content\/uploads\/2025\/07\/Painful-Feet-1024x768.jpg",800,600,true],"1536x1536":["https:\/\/tidolore.ch\/staging\/wp-content\/uploads\/2025\/07\/Painful-Feet-1536x1152.jpg",1536,1152,true],"2048x2048":["https:\/\/tidolore.ch\/staging\/wp-content\/uploads\/2025\/07\/Painful-Feet-2048x1536.jpg",2048,1536,true]},"rttpg_author":{"display_name":"admin","author_link":"https:\/\/tidolore.ch\/staging\/en\/author\/administrator\/"},"rttpg_comment":0,"rttpg_category":"<a href=\"https:\/\/tidolore.ch\/staging\/en\/category\/sindrome\/\" rel=\"category tag\">Sindrome<\/a>","rttpg_excerpt":"Peripheral neuropathy is a condition where the nerves in the arms and legs no longer function correctly. This can cause symptoms such as: When pain becomes a primary symptom, we refer to it as painful peripheral neuropathy. What are the most Common Causes? Neuropathies can have many causes. Among the most common are: How Does&hellip;","_links":{"self":[{"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/posts\/3431","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/comments?post=3431"}],"version-history":[{"count":13,"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/posts\/3431\/revisions"}],"predecessor-version":[{"id":4404,"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/posts\/3431\/revisions\/4404"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/media\/3432"}],"wp:attachment":[{"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/media?parent=3431"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/categories?post=3431"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tidolore.ch\/staging\/en\/wp-json\/wp\/v2\/tags?post=3431"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}