Even with a difficult diagnosis, no one should have to live with unnecessary pain.
What is it?
Cancer-related pain is pain that can occur at any stage of cancer, including:
- The initial stages of diagnosis
- Treatments (surgery, radiation therapy, chemotherapy, immunotherapy)
- The advanced stages
- Or even after recovery, as residual chronic pain
Or even after recovery, as residual chronic pain

How often does it occur?
According to scientific evidence:
- Approximately 30–50% of cancer patients experience pain during their illness.
- In advanced stages, the percentage can rise to 80%.
- In many cases, pain can be effectively controlled if treated by a specialist.
When do we intervene?
Uncontrolled cancer pain can have a significant impact on quality of life.
Early intervention by a pain therapist is helpful when:
- The pain does not respond to traditional medications.
- You want to reduce the dosage of opioids to limit their side effects.
- The pain is neuropathic or complicated.
- There are unacceptable side effects (sedation, constipation, nausea, confusion).
What treatments are available?
Drug treatment
- Anti-nociceptive drugs: paracetamol, NSAIDs
- Opioids in calibrated doses (morphine, oxycodone, fentanyl, tapentadol)
- Medications for neuropathic pain: gabapentin, pregabalin, duloxetine, amitriptyline
- Co-therapies: corticosteroids, antidepressants, anticonvulsants
Minimally Invasive Interventional Techniques
In selected cases:
- Ultrasound-guided or fluoroscopy-guided nerve blocks
- Pulsed or thermal radiofrequency
- Neurolytic blocks
- Catheters for continuous spinal infusion (epidural or intrathecal) in refractory cases
Other Integrated Approaches
- TENS and analgesic electrical stimulation
- Psychological support and cognitive-behavioral therapy
- Integrated palliative care, in collaboration with the oncologist
Treatment Objectives
- Reduce pain to a tolerable level
- Maintain maximum functionality and mental clarity
- Avoid or limit medication side effects
- Improve quality of life, at every stage of the illness